参考文献

1.Bhatt Band MeGee JOD. Chromsomal assignment of gene. In：In situ hybridization, Principles andpractice (Eds：Polak JM and McGee JOD)OxFord Science Publication, 1991：149～164

2.HopmanAHN et al.Interphase cytogenetics of solid tumors. In：In situ hybridisation, principlesand practice (Eds：Polak JM and McGee JOD)OxFord Science Pulication, 1991：165～186

3.WestJD.Sexing the human conceptus by in situ hybridization. In：In situ hybridisation, applicationto developmental biology and medicine (Eds：Harris N and Wilkinson DG).CombridgeUniversity Press, 1990：205～240

4.KochJ,et al. Oligonucleotide –priming methods for the chromosome –specificlabelling of alpha satellite DNA in situ.Chromosome, 1989, 98：259～265

5.EvaniViegas –Pequignot et al.Mapping of single – copy DNA sequences on humanchromsomes by in situ hybridisation with biotinylated probes：Enhancement of detectionsensitivity by intensifield - fluorescence digital –image mieroscopy. Proc NatlAcad Sci USA. 1989,86：582～586

6.MclarenA. Prenatal diagnosis before implantation：opportunities and problems. PrenatalDiagnosis, 1985；5：85～90

7.JulenJC, et al. Rapid prenatal diagnosis of Down’s syndrome with in situhybridisation of fluorescent DNA probe. Lancet , Ⅲ：863～864

8.MillarDS, ET AL. Normal blood cell values in the early and –trimester fetus：Prenatal Diagnosis, 1985, 5：367～373

9.BuggersJD, et al. The culture of mouse embryos in vitro. In ：Methods in mammalian Embryology,(Eds：Daniel JC Jr)San Francisco：Free man , 1971：86～116

10.HutchisonN et al. In situ hybridisation at the electron microscope level：Hybrid detection byautoradiography and colloidal gold, The J Cell Biology, 1982, 95：609～618

11. BinderM, et al. In situ hybridisation of the eletron microscope level：Localization of transcripts onultrathin sections of Lowicryl K4M-embedded tissue using biotinylated probesand Protein A-Gold Complexes. J. Cell Biology, 1986, 102：1646～1653

12.RothJM, et al. Enhancement of structural preservation and immunocytochemicalstaining in low temperature embedded pancreatic tissue. j Histochem. Cytochem,1981,29：663～667

13.LawrenceLB and Singer RH.Quantitative analysis of in situ hybridisation methods for thedetection of actin gene expression ,Nucleic Acids Res, 1985, 13：1777～1799

14.WeketerH deF,et al. Use of a biotinylated probe and in situ hybridisation for lightand electron microscopic localization of P[XB]0[/XB]mRNAin myelin –formingSchwann cells, Histochemistry, 1987, 86：441～444

15.CarlsmalarmE and Villger W. Low temperature embedding. In：Tehcniques in immunocytochemistry (EdsBullock GR and Petruoz P),Acad Press, 1989,4：29～44

16.焦仁杰，等.应用电镜原位分子杂交技术对腺病毒DNA在宿主细胞内进行定位.电子显微学报,1992,2：81～84